@Crux @bantam FYI: This issue should now be fixed via the very recently added Limits
property of Physics Constraints. This prevents bones from stretching to absurd dimensions, thus preventing infinitely large mesh bounds crashing Unity.
Please be sure to export your skeleton from the latest Spine 4.2-beta version and use the latest spine-unity 4.2-beta runtime, available for download here as usual:
https://esotericsoftware.com/spine-unity-download